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European examine confirms significance of biosecurity in HPAI management


Even when poultry are vaccinated in opposition to extremely pathogenic avian influenza (HPAI), biosecurity is an important software in illness management, in response to a brand new European examine that additionally checked out surveillance methods. 

Even when poultry are vaccinated in opposition to HPAI, biosecurity stays a vital factor of illness management.

This is without doubt one of the key messages in a second paper on the management of avian flu lately printed by the European Meals Security Authority (EFSA) and the European Reference Laboratory for Avian Influenza.

“Vaccination is an essential software within the struggle in opposition to avian influenza, and is really useful as a part of an built-in illness management strategy,” stated Frank Verdonck, head of EFSA’s Organic Hazards and Animal Well being and Welfare Unit. “Nonetheless, there’s a have to comply with up with a strategic surveillance scheme and implement measures to scale back the danger of virus transmission.

“Sustaining a excessive degree of biosecurity stays important, even when vaccination is used. Elevating consciousness amongst farm house owners and practitioners may help to make sure that any modifications in poultry manufacturing or elevated mortality are promptly reported and acted upon.”

Moreover, the authors stress the significance of finishing up post-vaccination surveillance of poultry. This won’t solely permit the detection of additional HPAI outbreaks, but additionally assist to exhibit freedom from the illness, and facilitate the protected motion of birds and poultry merchandise.

Within the paper, the consultants examined surveillance methods for each emergency and preventative vaccination. They went on to establish and advocate the optimum variety of animals to be examined, diagnostic methodology, and sampling interval for 3 poultry sorts — particularly laying hens, turkeys, and geese.

When the quantity of virus within the fowl’s blood is low following vaccination, the researchers counsel that extra delicate strategies be used.

The group’s earlier paper on HPAI vaccination of poultry was printed in October of 2023.

Wageningen examine investigates virus testing strategies

Fast checks carried out on farms can supply assist for the prognosis of avian flu viruses, in response to Wageningen Bioveterinary Analysis (WBVR) — a part of Wageningen College Analysis in The Netherlands. Nonetheless, these fast checks should not at the moment a passable alternative for polymerase chain response (PCR) checks carried out within the lab.

That is the principle conclusion from a current examine by which WBVR scientists explored the sensitivity and specificity of a number of fast checks for avian flu viruses.

Among the many drawbacks of a number of the checks was the feint line generated by a low virus focus was troublesome to see. Nonetheless, a PCR take a look at precisely confirmed the pattern was optimistic for the virus.

The examine discovered that each one the three most delicate checks detected all 16 virus H-subtypes, though they don’t permit the sort to be recognized.

Total, about 90% of the sector samples discovered to be optimistic by PCR had been additionally optimistic utilizing the fast checks. 

New HPAI outbreaks reported in Bulgaria, Hungary

Over the previous 10 days, simply two European states have confirmed new HPAI outbreaks in industrial poultry.

In Bulgaria, these have concerned 4 premises, in response to the Bulgarian Meals Security Company.

Affected for the reason that finish of March have been two laying flocks comprising round 25,000 and 154,000 laying hens within the central province of Haskovo and in Plovdiv within the south, respectively. Additionally in Haskovo was an outbreak involving 300,000 broilers, whereas the opposite outbreak was in an unregistered combined flock of round 100 poultry within the adjoining province of Kardzhali.

Based mostly on official notifications to the World Organisation for Animal Well being (WOAH), 10 outbreaks linked to the H5N1 HPAI virus serotype have occurred in Bulgaria this 12 months, as much as the tip of March.

Following a quick hiatus, the identical HPAI virus variant has been detected once more in two counties of Hungary.

Within the final 10 days, the nationwide animal well being company has notified WOAH about 4 outbreaks in Bekes within the southeast of the nation, and one in neighboring Jasz-Nagykun-Szolnok. The reviews don’t embody particulars of flock sizes or fowl sorts.

Ten H5N1 HPAI outbreak sequence in Hungary between November of 2023 and January this 12 months affected a complete of 76 premises with greater than 1.6 million poultry throughout a lot of the nation, primarily based on reviews to WOAH. 

Overview of the HPAI scenario in European poultry, captive birds

Because the begin of 2024, 16 European nations have collectively recorded 138 HPAI outbreaks in industrial poultry flocks (as of April 12).

That is in accordance to the Animal Illness Data System from the European Fee (EC). It displays the illness scenario in European Union (EU) member states and neighboring nations.

In contrast with the earlier version dated April 5, the outbreak complete rose by three — all in Bulgaria.

The best nationwide complete for the reason that begin of the 12 months is 55 outbreaks in Moldova, adopted by Poland (with 25). Neither nation has added to its complete since early March.

Throughout the entire of 2023, the EC System recorded a complete of 521 outbreaks in poultry throughout 24 nations.

In a separate class of “captive birds” the EC System data HPAI outbreaks in non-commercial poultry, zoos, and comparable premises.

Seven European nations have registered a complete of 46 outbreaks affecting this inhabitants in 2024 (as of April 12). No new circumstances on this class have been reported since mid-March.

For comparability, 15 nations registered a complete of 99 HPAI outbreaks amongst captive birds final 12 months.   

Sluggish rise in circumstances amongst wild animals in Europe

There are indicators that the height season for HPAI infections within the area’s wild birds has handed.

To this point in 2024, a complete of 379 outbreaks have been registered with the EC System on this inhabitants by 26 nations (as of April 12).

Whereas a primary case of the 12 months has been recorded in Latvia, the general outbreak complete has risen by simply six for the reason that earlier System version dated April 5.

Three of those had been confirmed in Germany, which additionally has the very best complete so far at 133. Subsequent come Denmark (72) and Romania (23), however neither has added to its complete over the earlier week.

Additional circumstances in wild birds have been registered with the EC by Norway (two outbreaks) and Poland (one).

Not included in the EC System is the Nice Britain, the place the veterinary authority has notified WOAH about one extra an infection in a wild fowl linked to the H5N1 virus variant.

Earlier this month, two purple foxes examined optimistic for the H5N1 HPAI virus close to the German metropolis of Hamburg. Based mostly on WOAH reviews, Germany has recorded a complete of 21 such circumstances in “uncommon hosts” (non-avian species) over the previous two years.  

View our persevering with protection of the world avian influenza scenario.

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